A Facile One-Pot Synthesis of Functionalized N-Hydroxypyrrole Mediated by Vinyl-Triphenylphosphonium Salt
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Abstract:
Protonation of the reactive intermediates generated in the raction between dalkyl acetylenedicarboxylates and triphenylphosphine by isonitrosoacetophenone leads to vinyltriphenylphosphonium salts, which undergo intramolecular Wittig reaction to produce dalkyl 4-phenyl-N-hydroxypyrrole-2,3-dicarboxylates in moderate yields.
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Journal title
volume 17 issue 1
pages 38- 41
publication date 1998-06-01
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